Human Sandwich TIMP-1 ELISA Kit

Product Detail

Brand	MultiSciences
CatNum	70-EK1138
Product Name	Human TIMP-1 ELISA Kit
Customs Name	Human TIMP-1 ELISA Kit
Application	ELISA
Reactivity	Human
Assay Type	Sandwich ELISA
Suitable Sample Type	serum, plasma, cell culture supernates
Format	96-well strip plate
Storage	4? (unopened) standard stored at -20?, others stored at 4? (opened)
Shipping Condition	4?
Sample Volume	10 µl (prediluted)
Sensitivity	3.94 pg/ml
Standard Curve Range	31.25 - 2000 pg/ml
Spike Recovery Range	-
Mean Spike Recovery	-
CV of Intra plate	4.9 % - 5.4 %
CV of Inter plate	6.4 % - 7.3 %
Components	96-well polystyrene microplate coated with a monoclonal antibody against TIMP-1 Human TIMP-1 Standard, lyophilized TIMP-1 Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers
Describtion	This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human TIMP-1. The Human TIMP-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Tissue inhibitor of matrix metalloprotease-1 (TIMP-1) is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Increased expression of TIMP-1 has been found to be associated with worse prognosis of various tumors, such as laryngeal carcinoma or melanoma.




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